NIST REFPROP

In the thermodynamic module also FLUIDCAL is used by CONVAL®

This program, developed by the National Institute of Standards and Technology (NIST), calculates the thermodynamic and transport properties of industrially important fluids and their mixtures. REFPROP is a Program, not a Database Containing Measurements. The REFPROP "database" is actually a program and does not contain any experimental information, aside from the critical and triple points of the pure fluids. The program uses equations for the thermodynamic and transport properties to calculate the state points of the fluid or mixture. These equations are the most accurate equations available worldwide. Their high accuracy is obtained through many coefficients in the equations, and thus the calculation speed will be slower than other equations such as the Peng-Robinson cubic equations. The equations are generally valid over the entire vapor and liquid regions of the fluid, including supercritical states; the upper temperature limit is usually near the point of decomposition of the fluid, and the upper pressure (or density) limit is defined by the melting line of the substance.

REFPROP is based on the most accurate pure fluid and mixture models currently available. It implements three models for the thermodynamic properties of pure fluids:  equations of state explicit in Helmholtz energy, the modified Benedict-Webb-Rubin equation of state, and an extended corresponding states (ECS) model.  Mixture calculations employ a model that applies mixing rules to the Helmholtz energy of the mixture components; it uses a departure function to account for the departure from ideal mixing.  Viscosity and thermal conductivity are modeled with either fluid-specific correlations, an ECS method, or in some cases the friction theory method. 

Fluids and mixtures which are embedded in REFPROP database together with their range of validity:

Short name

CAS number

Full chemical name

EOC limits

acetone 67-64-1 propanone 178.5-550 K, 700 MPa
ammonia 7664-41-7 ammonia 195.495-700 K, 1000 MPa
argon 7440-37-1 argon 83.8058-2000 K, 1000 MPa
benzene 71-43-2 benzene 278.674-725 K, 500 MPa
butane 106-97-8 n-butane 134.895-575 K, 200 MPa
butene 106-98-9 1-butene 87.8-525 K, 70 MPa
carbon dioxide 124-38-9 carbon dioxide 216.592-2000 K, 800 MPa
carbon monoxide 630-08-0 carbon monoxide 68.16-500 K, 100 MPa
carbonyl sulfide 463-58-1 carbon oxide sulfide 134.3-650 K, 50 MPa
cis-butene 590-18-1 cis-2-butene 134.3-525 K, 50 MPa
cyclohexane 110-82-7 cyclohexane 279.47-700 K, 250 MPa
cyclopentane 287-92-3 cyclopentane 179.7-550 K, 250 MPa
cyclopropane 75-19-4 cyclopropane 273-473 K, 28 MPa
D4 556-67-2 octamethylcyclotetrasiloxane 290.25-673 K, 30 MPa
D5 541-02-6 decamethylcyclopentasiloxane 300-673 K, 30 MPa
D6 540-97-6 dodecamethylcyclohexasiloxane 270.2-673 K, 30 MPa
decane 124-18-5 decane 243.5-675 K, 800 MPa
deuterium 7782-39-0 deuterium 18.724-600 K, 2000 MPa
diethyl ether 60-29-7 diethyl ether 270-500 K, 40 MPa
dimethyl carbonate 616-38-6 dimethyl ester carbonic acid 277.06-600 K, 60 MPa
dimethylether 115-10-6 methoxymethane 131.66-525 K, 40 MPa
dodecane 112-40-3 dodecane 263.6-700 K, 700 MPa
ethane 74-84-0 ethane 90.368-675 K, 900 MPa
ethanol 64-17-5 ethyl alcohol 159-650 K, 280 MPa
ethylbenzene 100-41-4 phenylethane 178.2-700 K, 60 MPa
ethylene 74-85-1 ethene 103.986-450 K, 300 MPa
fluorine 7782-41-4 fluorine 53.4811-300 K, 20 MPa
heavy water 7789-20-0 deuterium oxide 276.97-800 K, 100 MPa
helium 7440-59-7 helium-4 2.1768-2000 K, 1000 MPa
heptane 142-82-5 heptane 182.55-600 K, 100 MPa
hexane 110-54-3 hexane 177.83-600 K, 100 MPa
hydrogen (normal) 1333-74-0 hydrogen (normal) 13.957-1000 K, 2000 MPa
hydrogen chloride 7647-01-0 hydrogen chloride 155-330 K, 20 MPa
hydrogen sulfide 7783-06-4 hydrogen sulfide 187.7-760 K, 170 MPa
isobutane 75-28-5 2-methylpropane 113.73-575 K, 35 MPa
isobutene 115-11-7 2-methyl-1-propene 132.4-550 K, 50 MPa
isohexane 107-83-5 2-methylpentane 119.6-550 K, 1000 MPa
isooctane 540-84-1 2,2,4-trimethylpentane 165.77-600 K, 1000 MPa
isopentane 78-78-4 2-methylbutane 112.65-500 K, 1000 MPa
krypton 7439-90-9 krypton 115.775-750 K, 200 MPa
m-xylene 108-38-3 1,3-dimethylbenzene 225.3-700 K, 200 MPa
MD2M 141-62-8 decamethyltetrasiloxane 205.2-673 K, 30 MPa
MD3M 141-63-9 dodecamethylpentasiloxane 192-673 K, 30 MPa
MD4M 107-52-8 tetradecamethylhexasiloxane 300-673 K, 30 MPa
MDM 107-51-7 octamethyltrisiloxane 187.2-673 K, 30 MPa
methane 74-82-8 methane 90.6941-625 K, 1000 MPa
methanol 67-56-1 methanol 175.61-620 K, 800 MPa
methyl linoleate 112-63-0 methyl (Z,Z)-9,12-octadecadienoate 238.1-1000 K, 50 MPa
methyl linolenate 301-00-8 methyl (Z,Z,Z)-9,12,15-octadecatrienoate 218.65-1000 K, 50 MPa
methyl oleate 112-62-9 methyl cis-9-octadecenoate 253.47-1000 K, 50 MPa
methyl palmitate 112-39-0 methyl hexadecanoate 302.71-1000 K, 50 MPa
methyl stearate 112-61-8 methyl octadecanoate 311.84-1000 K, 50 MPa
methylcyclohexane 108-87-2 methylcyclohexane 146.7-600 K, 500 MPa
MM 107-46-0 hexamethyldisiloxane 273-673 K, 30 MPa
neon 7440-01-9 neon 24.556-700 K, 700 MPa
neopentane 463-82-1 2,2-dimethylpropane 256.6-550 K, 200 MPa
nitrogen 7727-37-9 nitrogen 63.151-2000 K, 2200 MPa
nitrogen trifluoride 7783-54-2 nitrogen trifluoride 85-500 K, 50 MPa
nitrous oxide 10024-97-2 dinitrogen monoxide 182.33-525 K, 50 MPa
nonane 111-84-2 nonane 219.7-600 K, 800 MPa
o-xylene 95-47-6 1,2-dimethylbenzene 247.985-700 K, 70 MPa
octane 111-65-9 octane 216.37-600 K, 100 MPa
orthohydrogen 1333-74-0o orthohydrogen 14.008-1000 K, 2000 MPa
oxygen 7782-44-7 oxygen 54.361-2000 K, 82 MPa
p-xylene 106-42-3 1,4-dimethylbenzene 286.4-700 K, 200 MPa
parahydrogen 1333-74-0p parahydrogen 13.8033-1000 K, 2000 MPa
pentane 109-66-0 pentane 143.47-600 K, 100 MPa
perfluorobutane 355-25-9 decafluorobutane 189-500 K, 30 MPa
perfluoropentane 678-26-2 dodecafluoropentane 148.363-500 K, 30 MPa
propane 74-98-6 propane 85.525-650 K, 1000 MPa
propylcyclohexane 1678-92-8 n-propylcyclohexane 178.2-650 K, 50 MPa
propylene 115-07-1 propene 87.953-575 K, 1000 MPa
propyne 74-99-7 propyne 273-474 K, 32 MPa
sulfur dioxide 7446-09-5 sulfur dioxide 197.7-525 K, 35 MPa
sulfur hexafluoride 2551-62-4 sulfur hexafluoride 223.555-625 K, 150 MPa
toluene 108-88-3 methylbenzene 178-700 K, 500 MPa
trans-butene 624-64-6 trans-2-butene 167.6-525 K, 50 MPa
trifluoroiodomethane 2314-97-8 trifluoroiodomethane 120-420 K, 20 MPa
undecane 1120-21-4 undecane 247.541-700 K, 500 MPa
water 7732-18-5 water 273.16-2000 K, 1000 MPa
xenon 7440-63-3 xenon 161.405-750 K, 700 MPa
1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl)-3-pentanone 756-13-8 Dodecafluoro-2-methylpentan-3-one 165-500 K, 50 MPa
R11 75-69-4 trichlorofluoromethane 162.68-625 K, 30 MPa
R113 76-13-1 1,1,2-trichloro-1,2,2-trifluoroethane 236.93-525 K, 200 MPa
R114 76-14-2 1,2-dichloro-1,1,2,2-tetrafluoroethane 273.15-507 K, 21 MPa
R115 76-15-3 chloropentafluoroethane 173.75-550 K, 60 MPa
R116 76-16-4 hexafluoroethane 173.1-425 K, 50 MPa
R12 75-71-8 dichlorodifluoromethane 116.099-525 K, 200 MPa
R1216 116-15-4 hexafluoropropene 117.654-400 K, 12 MPa
R123 306-83-2 2,2-dichloro-1,1,1-trifluoroethane 166-600 K, 40 MPa
R1233zd(E) 102687-65-0 1-chloro-3,3,3-trifluoroprop-1-ene 195.15-550 K, 100 MPa
R1234yf 754-12-1 2,3,3,3-tetrafluoroprop-1-ene 220-410 K, 30 MPa
R1234ze(E) 29118-24-9 trans-1,3,3,3-tetrafluoropropene 168.62-420 K, 20 MPa
R124 2837-89-0 1-chloro-1,2,2,2-tetrafluoroethane 120-470 K, 40 MPa
R125 354-33-6 pentafluoroethane 172.52-500 K, 60 MPa
R13 75-72-9 chlorotrifluoromethane 92-403 K, 35 MPa
R134a 811-97-2 1,1,1,2-tetrafluoroethane 169.85-455 K, 70 MPa
R14 75-73-0 tetrafluoromethane 120-623 K, 51 MPa
R141b 1717-00-6 1,1-dichloro-1-fluoroethane 169.68-500 K, 400 MPa
R142b 75-68-3 1-chloro-1,1-difluoroethane 142.72-470 K, 60 MPa
R143a 420-46-2 1,1,1-trifluoroethane 161.34-650 K, 100 MPa
R152a 75-37-6 1,1-difluoroethane 154.56-500 K, 60 MPa
R161 353-36-6 fluoroethane 130-450 K, 5 MPa
R21 75-43-4 dichlorofluoromethane 200-473 K, 138 MPa
R218 76-19-7 octafluoropropane 125.45-440 K, 20 MPa
R22 75-45-6 chlorodifluoromethane 115.73-550 K, 60 MPa
R227ea 431-89-0 1,1,1,2,3,3,3-heptafluoropropane 146.35-475 K, 60 MPa
R23 75-46-7 trifluoromethane 118.02-475 K, 120 MPa
R236ea 431-63-0 1,1,1,2,3,3-hexafluoropropane 240-412 K, 6 MPa
R236fa 690-39-1 1,1,1,3,3,3-hexafluoropropane 179.6-400 K, 70 MPa
R245ca 679-86-7 1,1,2,2,3-pentafluoropropane 191.5-450 K, 10 MPa
R245fa 460-73-1 1,1,1,3,3-pentafluoropropane 171.05-440 K, 200 MPa
R32 75-10-5 difluoromethane 136.34-435 K, 70 MPa
R365mfc 406-58-6 1,1,1,3,3-pentafluorobutane 239-500 K, 35 MPa
R40 74-87-3 methyl chloride 230-630 K, 100 MPa
R41 593-53-3 fluoromethane 129.82-425 K, 70 MPa
RC318 115-25-3 octafluorocyclobutane 233.35-623 K, 60 MPa
RE143a 421-14-7 methyl trifluoromethyl ether 240-420 K, 7.2 MPa
RE245cb2 22410-44-2 methyl-pentafluoroethyl-ether 250-500 K, 20 MPa
RE245fa2 1885-48-9 2,2,2-trifluoroethyl-difluoromethyl-ether 250-500 K, 400 MPa
RE347mcc 375-03-1 methyl-heptafluoropropyl-ether 250-500 K, 20 MPa